• It can be highly difficult to translate the [popover id="IBYOAu-X6ZA6x3aV" lave="genome"] of?complex organisms?into their?proteome
• Determining the proteome of humans is difficult as large amounts of?non-coding DNA?are present in human genomes
  • It can be very?hard to identify?these sections of DNA from the coding DNA

   

• The presence of?regulatory genes?and the process of?alternative splicing?in human genomes also affects gene expression and the synthesis of proteins
• The proteome is?larger?than the genome due to:
  • Alternative splicing
  • Post-translational modification of proteins (often takes place in the Golgi apparatus)

   

Alternative splicing allows for a single gene to produce multiple proteins

The proteome is larger than the genome