有“中學生諾獎”之稱的再生元科學天才獎STS公布了TOP300的獲獎名單，有方學子今年也在STS中取得了佳績！讓我們恭喜他們！
有方學員STS喜報
作為全美歷史最悠久、最負盛名的科創賽事，每年都有超50%的STS TOP300入圍者被哈耶普斯麻錄取！
今年共有來自美國46個州、華盛頓特區、北馬里亞納群島、波多黎各及16個國家的826所高中的超2600名學生參與了STS，其中來自美國34個州、華盛頓特區和中國的203所美國及國際高中的學生斬獲Top300的榮譽！
下面就跟隨小師姐就一起來看看2025-26 STS TOP300名單吧！
以下獲獎名單來源于STS官網：
https://www.societyforscience.org/regeneron-sts/2026-scholars/
25-26 Regeneron STS Top300
Meghana Addanki, Age: 17
McNair Academic High School, New Jersey
Project Title: Efficient Energy Harvesting Using Biomaterials: Fabrication of a ZnO-Modified Eggshell Membrane and Cotton Fabric-Based Piezo-Tribo Hybrid Generator
Aryana Adur, Age: 17
Jericho Senior High School, New York
Project Title: Therapeutic Modulation of a Novel Neuroepithelial Circuit by Larazotide Acetate and Neuregulin-1 Restores Epithelial Barrier Integrity in Food Allergy
Anusha Agarwal, Age: 17
Thomas Jefferson High School for Science and Technology, Virginia
Project Title: Multigrid-Inspired Neural Operators for Real-Time Brain Biomechanics Prediction With Spectrally-Aware Learning
Arjun Agarwal, Age: 18
Jesuit High School, Oregon
Project Title: Semisimplifications of αp-Equivariant GLn-Modules
Anchita Agrawal, Age: 17
Jericho Senior High School, New York
Project Title: Characterizing Convergent Transcriptomic Impacts of Norepinephrine Across Breast Cancer Grades via “Element AVITI-24”
Avyakt Agrawal, Age: 17
Woodward Academy College, Georgia
Project Title: A Novel Adaptive Learning Framework Integrating Item Response Theory, Bayesian Knowledge Tracing and Deep Learning With Confidence-Calibrated Feedback
Lakshmi Agrawal, Age: 18
Stanford University Online High School, California
Project Title: Stormwater Remediation of 6PPD and 6PPD-Quinone Using Citric Acid and Aluminum-Crosslinked Nanocellulose Hydrosponges
Amogh Akella, Age: 17
Westwood High School, Texas
Project Title: Diameter Bounds for Friends-and-Strangers Graphs
Sebastian Rae Alexis, Age: 17
Northwood High School, California
Project Title: A Novel Framework for Stegomalware Detection Using Kolmogorov Complexity
Anish Anand, Age: 18
Palos Verdes Peninsula High School, California
Project Title: A Novel Wireless Charging System for Pacemakers Using 2.4 GHz EM Waves
Aniruth Ananthanarayanan, Age: 18
Texas Academy of Mathematics and Science, Texas
Project Title: Cutting Too Deep: Tracking a Decade of Benign Lung Resections After the Rise of LDCT Cancer Screening
Noah-Duro Christopher Andre, Age: 18
American Heritage School, Florida
Project Title: Isolating, Screening and Identifying Bacteria and Fungi Found Within Mangrove Soil in Florida for Accessible Antimicrobial Natural Products
Rohan Arni, Age: 17
High Technology High School, New Jersey
Project Title: Using Deep Learning for Robust Classification of Fast Radio Bursts
Adhithi Arun, Age: 18
Livingston High School, New Jersey
Project Title: Platelets Promote Multiple Myeloma Cell Survival and Immune Evasion Through Soluble Factors and NK Cell Modulation
Shruti Arun, Age: 18
Cherry Creek High School, Colorado
Project Title: On the Double of an Endymion Algebra in Characteristic 2
Matthew Bace, Age: 18
The Governor’s Academy, Massachusetts
Project Title: Protecting Native Forest Ecosystems: Using AI-Powered Drones for Identifying and Mapping Invasive Insect Populations
Ella Jennings Baker, Age: 18
Spring Valley High School, South Carolina
Project Title: Utilizing the CARRGO Model To Compare the Efficacy of HER2- and EGFR-Targeting CAR-NK Cells on Glioblastoma
Vedant Balani, Age: 17
Jericho Senior High School, New York
Project Title: Hurricane Forecasting Using Comprehensive Multivariable Machine Learning Modeling With Atmospheric Temperatures, Polar Motion and Sunspot Numbers
Pravin Balasingam, Age: 17
Los Gatos High School, California
Project Title: Novel Machine Learning Approach To Identify Brain-Behavior Relationships for Core Autistic Traits
Abhigya Bandugula, Age: 18
Lynbrook High School, California
Project Title: Comparison of RNA-Seq Data From Primary and Recurrent Acute Myeloid Leukemia Patients
Avani Tara Bansal, Age: 18
The Potomac School, Virginia
Project Title: A Novel Pneumatic Silicone Sleeve for Transhumeral Prostheses That Autonomously Regulates and Adjusts to Socket–Limb Pressure To Improve Amputee Comfort
Summerville Beckford, Age: 17
Ossining High School, New York
Project Title: Immersive Virtual Reality Paired With a Stress Mindset Intervention Improves Stress Management in Adolescents
Dhroov Bharatia, Age: 17
Plano Senior High School, Texas
Project Title: AutoMates: Automating With Self-Learning Intelligent Agents
Mishika Bhatia, Age: 17
Rock Canyon High School, Colorado
Project Title: Saw Palmetto-Induced Inhibition of the 5α-Reductase Pathway as a Clinical Treatment for PCOS Symptoms
Allie Blocher, Age: 18
The Lakeside School, Washington
Project Title: Clinical Validation of a Novel $50 Multiple-Pinhole Optometer for Globalizing Vision Testing: Accommodation Bias Drives Dual-Target Innovation
Noelie Roxane Boquet Couderc, Age: 17
Harrison High School, New York
Project Title: Determining if Radioprotection Can Be Enhanced Through the Use of Deinococcus radiodurans MDP and Tardigrada Dsup Protein: Implications for Space Exploration
Srishti Boral, Age: 17
Eastlake High School, Washington
Project Title: Computational Design of Small-Molecule Activators of the AtlA Autolysin To Induce Internal Cell Death in Methicillin-Resistant Staphylococcus aureus
Thanh Can, Age: 17
Jackson Reed High School, DC
Project Title: Measures on Colored Binary Tree Structures and Applications to Tensor Categories
Albert Cao, Age: 18
Centennial High School, Maryland
Project Title: Machine Learning Prediction of On/Off Target-Driven Clinical Adverse Events
Tristan Rei Cao, Age: 18
Stargate School, Colorado
Project Title: Tailoring Quantum Phases via Magneto-Synthesis in a Spin–Orbit-Coupled Trimer Lattice
Abhiram Chalamalasetty, Age: 17
Canyon Crest Academy, California
Project Title: TubercuProbe: A Cross-Attention Graph-Sequence Model for Prioritizing Compound Probes in Mycobacterium tuberculosis
Alexander Ang Chan, Age: 18
Boston Latin School, Massachusetts
Project Title: Gut Microbial Composition and Function Associated With Antidepressant Response: Evidence From a Community-Based Cohort of Older Adults
Tessla Chan, Age: 18
Roslyn High School, New York
Project Title: Investigating PELO as a Novel Synthetic Lethal Target Across Multiple Molecular Subtypes of Gastrointestinal Cancers
Max Charney, Age: 18
Byram Hills High School, New York
Project Title: Harnessing Millions of Consumer Reviews To Reveal Societal Trends at an Unprecedented Scale: Two Proof-of-Concept Studies for a Novel Computational Social Science Approach
Soumik Chemudupati, Age: 17
Liberal Arts and Science Academy, Texas
Project Title: Effectiveness of Amygdala Hijack Threat Cues for Interpretable Phishing Email Detection: A Comparison of Machine Learning, Deep Learning and Large Language Models
Darren Chen, Age: 18
George W. Hewlett High School, New York
Project Title: Watching Others, Withholding Self: How Vicarious Embarrassment Relates to Adolescents’ Online Self-Presentation and Willingness To Share
Hailan Chen, Age: 18
Stuyvesant High School, New York
Project Title: Class IIa Histone Deacetylase HDAC7 Acts as Master Regulator of STAT3 Inflammatory Pathways and HMGCS1 Cholesterol Synthesis Pathways in Reactive Astrocytes
Hayden Chen, Age: 17
Del Norte High School, California
Project Title: A Novel Framework for the Discovery of MAP Kinase-Activated Protein Kinase 2 (MAPKAPK2) Inhibitors Using a Multi-Feature Deep Learning Ensemble
Joshua Chen, Age: 18
Panther Creek High School, North Carolina
Project Title: Exploring Nucleolar Protein 4 (NOL4) as a Novel Biomarker in Neuroendocrine Prostate Cancer Using Single-Cell RNA Sequencing
Rachel Chen, Age: 18
Marlborough School, California
Project Title: The Dual Canonical Basis in the Spin Representation via the Temperley-Lieb Algebra
Shin-En Chen, Age: 17
The King’s Academy, California
Project Title: Characterization of HBV-Host Junction Profile by HBV-Targeted NGS in Urine for Early Detection of Recurrent Hepatocellular Carcinoma and Disease Management
Sophia Chen, Age: 18
Farragut High School, Tennessee
Project Title: Explainable AI-Guided Virtual Experiments Reveal How DNA Sequence Context Shapes Gene Regulation
Vincent Chen, Age: 17
Stuyvesant High School, New York
Project Title: Harnessing Ferroelectric HfO2-Modified Carbon Nanotube Membranes for Efficient Hydrogen Atom Generation and Transport Toward Sustainable Ammonia Synthesis
Bing Cheng, Age: 18
Trabuco Hills High School, California
Project Title: Increasing Propeller Performance: Investigating the Optimization and Potential of a Novel Propeller Concept Through Computational Fluid Simulation, Experimental Testing Rig and Commercial Drone Integration
Lisa Cheng, Age: 17
Harvard-Westlake School, California
Project Title: Structure-Based D-Peptide α-Synuclein Inhibitor: Tackling Solubility, Specificity and Bioavailability Challenges in Parkinson’s Disease Therapy
Linus Chen-Plotkin, Age: 18
Germantown Friends School, Pennsylvania
Project Title: Predictability and Statistical Memory in Classical Sonatas and Quartets
Ryka Chopra, Age: 17
Mission San Jose High School, California
Project Title: Designing Incentive-Compatible Cooperation for the Global Commons: A Reinforcement Learning-Integrated Mechanism Design Framework for Arctic Conservation
Colin Jie Chu, Age: 18
The Nueva School, California
Project Title: Frequency-Based Parameterization of Semi-Empirical Models for State-of-Health Estimation in Lithium-Ion Batteries in Electric Vehicles
Lindsay Coady, Age: 17
Byram Hills High School, New York
Project Title: The Identification of Anti-Complement Autoantibodies in Schizophrenia: A Novel Gene by Environment Hypothesis of Autoimmunity in Neuropsychiatric Disorders
Mason Corey, Age: 17
Kingsway Regional High School, New Jersey
Project Title: AI-Powered Thermal Fingerprinting: Predicting PLA Tensile Strength Through Schlieren Imaging
Jorge Covarrubias, Age: 17
Harvest Preparatory Academy Yuma, Arizona
Project Title: káktosPatch: Monitoring Necrosis in Carnegiea gigantea (Saguaro Cactus) Using an Engineered Smart Bandage and Mobile Application
Arnav Dagar, Age: 17
Canyon Crest Academy, California
Project Title: ARFSNet–Deep Learning for Amblyopia Risk Factor Screening
Shaunak Dalal, Age: 17
Hershey High School, Pennsylvania
Project Title: Time-Series Deep Learning and Conformal Prediction for Improved Sepsis Diagnosis in Primarily Non-ICU Hospitalized Patients
Rohan Dash, Age: 17
Pine View School, Florida
Project Title: Controllable Multi-Objective Neural Architecture Search via Decision Transformers
Jack D’Cruz, Age: 18
University School, Ohio
Project Title: Immunoproteasome Activation Enhances Melanoma Immunogenicity by Increasing HLA and MAGE-A1 Antigen Presentation
Shaumprovo Debnath, Age: 18
Keystone School, Texas
Project Title: From Thought to Speech: Integrating Low Cost EEGs With AI To Decode Neural Language Signals in Neurologically Intact Non-Verbal Neuromuscular Patients
Jashvi Desai, Age: 18
Yorktown High School, New York
Project Title: Neuroinflammatory Signatures and Compensatory Prefrontal Mechanisms in Long COVID-19: Insights From 7T MRI and Cognitive Modeling
Mythreya Dharani, Age: 18
Bergen County Academies, New Jersey
Project Title: I2-CISSP: An Interpretable Machine Learning Framework for Robust and Practical Prediction of Cisplatin Response in Human Tumors
Bryan Ding, Age: 18
Bergen County Academies, New Jersey
Project Title: Adipocyte-Like Cells as a Novel Source of Myofibroblasts in Pulmonary Fibrosis
Angela Dong, Age: 18
Poolesville High School, Maryland
Project Title: Teaching Robots New Tasks With One Picture (TROP): A Use Case Development Using Edge AI Perception
Andrei Dorobantu, Age: 17
Montgomery Blair High School, Maryland
Project Title: Single-Cell Machine Learning Identifies Functionally Distinct Cytokine Families in Macrophages
Jonathan Du, Age: 18
Los Altos High School, California
Project Title: An Unrestricted Notion of the Finite Factorization Property
Isabel Kelly Duffy, Age: 18
American Heritage School, Florida
Project Title: Laccase-Mediated Degradation of Polyethylene and Polystyrene via Invasion and Ingestion by Pleurotus ostreatus
Patricia Duffy, Age: 18
American Heritage School, Florida
Project Title: Neuroprotective Effects of Astaxanthin in Caenorhabditis elegans Amyotrophic Lateral Sclerosis Models
Leanne Fan, Age: 18
Westview School, California
Project Title: Photobiomodulation on In Vivo and In Vitro Wound Models Under Simulated Microgravity for Future Space Travel
Winston Derek-Xu Fan, Age: 18
West High School, Iowa
Project Title: PsychSPT: A Novel AI System for Mental Health Assessment Using Large Language Models (LLMs)
Nishini Fernando, Age: 18
Dunbar High School, Florida
Project Title: Comprehensive In Vitro Evaluation of Antidiabetic, Antioxidant, Cytotoxic and Wound-Healing Activities of Six Native Plant Species: Prelude to Novel Drug Discovery
Nolan John Francis, Age: 18
Staples High School, Connecticut
Project Title: Vitamin D3 Supplementation Ameliorates Muscle Degeneration Through Calcium Regulation in a Caenorhabditis elegans Model of Duchenne Muscular Dystrophy
Warren Fu, Age: 17
Horace Greeley High School, New York
Project Title: Biophysical and Genomic Drivers of Targeted Therapy Resistance: Analysis of Growth Dynamics in Non-Small Cell Lung Cancer
Fillip Fuňák, Age: 18
North Carolina School of Science and Mathematics, North Carolina
Project Title: Design, Synthesis and Testing of a Novel 3,5-Dimethoxycinnamic Acid-Based Cathepsin C Inhibitor for the Treatment of Inflammatory Bowel Disease
Samanyu Krishna Ganesh, Age: 18
The Westminster Schools, Georgia
Project Title: Characterizing Variations in the Ruelle Zeta Function Under Conformal Perturbations to the Metrics of Negatively Curved Riemannian 2-Manifolds
Yujun Ge, Age: 18
Cerritos High School, California
Project Title: Transforming Assistive Communication: An AI and NLP-Powered Machine Learning Framework for Contextual AAC
Anand Sebastian George, Age: 17
University School of Milwaukee, Wisconsin
Project Title: Prediction of Infection Risk in Multiple Myeloma Patients Treated With Bispecific Antibodies: Neural Network and Ensemble Approaches
Cyrus Ghane, Age: 17
The Harker School, California
Project Title: Toward a Unified Model of the Macaque Cortex With Multi-Scale Spatiotemporal-Neurochemical Integration
Shanice Lashay Gibson, Age: 18
Granbury High School, Texas
Project Title: Design and Validation of a Biomimetic Melanin-Rich Skin Model for Measuring Hydration Retention and Barrier Function Using Low-Cost Sensor Technologies
Scarlet Gitelson, Age: 17
Latin School of Chicago, Illinois
Project Title: Detecting Stellar and Disk Winds Through Absorption Spectroscopy of Black Hole High Mass X-Ray Binary Cygnus X-1
Xavier Gitre, Age: 18
Blacksburg High School, Virginia
Project Title: Partying Parulidae: Interspecific Social Networks of Parulidae Warblers in Active Migratory Passage
Jiaxuan Gong, Age: 18
Northville High School, Michigan
Project Title: Gaussian-Process Generative Model for the QCD Equation of State
Alisa Victoria Gordon, Age: 17
Brooklyn Technical High School, New York
Project Title: The Effects of Acute and Chronic Sleep Deprivation on Metabolic Dysregulation via AgRP Neuronal Activity in the Arcuate Nucleus
Michael Guan, Age: 18
Miami Palmetto Senior High School, Florida
Project Title: Feature-Based Multi-Modal Machine Learning for Diabetes Classification in AI-READI
Andrew Guo, Age: 18
Gwinnett School of Mathematics, Science and Technology, Georgia
Project Title: Investigating the Role of Intrinsic snoRNA Properties on Ribosomal RNA Modification Heterogeneity
Johnny Guo, Age: 18
Choate Rosemary Hall, Connecticut
Project Title: Global Spatiotemporal Analysis of Interactions Between Urban Heat Islands and Heat Waves
Kevin Guo, Age: 17
Horace Greeley High School, New York
Project Title: Development of a SpyTag/SpyCatcher-Based Antibody-siRNA Internalization Assay for High-Throughput Screening
Danika Gupta, Age: 17
The Harker School, California
Project Title: Using AI To Clean Water: Leveraging Large Language Models for Mycoremediation Data Extraction and Modeling
Shivam Gupta, Age: 16
Friendswood High School, Texas
Project Title: Vision AI: A Novel and Cost-Effective Wearable Assistive System for the Visually Impaired Leveraging AI and Machine Vision
Liyang Han, Age: 18
Brookfield Central High School, Wisconsin
Project Title: A Multimodal AI-Powered Diagnostic and Robot-Assisted Rehabilitation System for Parkinson’s Patients
Michael Han, Age: 18
Lexington High School, Massachusetts
Project Title: Improved Bounds for Novelty Games
Karthika Hariprasad, Age: 17
Paul Laurence Dunbar High School, Kentucky
Project Title: A Novel Skin Cancer Detector Using Machine Learning
David Zhang He, Age: 18
Westview School, California
Project Title: An Integrated Analysis of Marine Polyurethane Microplastic Degradation With Genetically Engineered Bacterial Biofilms
Connor Hill, Age: 17
Delta High School, Pennsylvania
Project Title: The Complete Set of Noble Polyhedra
Brendan Hirshorn, Age: 18
Regis High School, New York
Project Title: Explainable Inverse Design of Aluminium and Cobalt Alloys Through Hierarchical Generative Modeling
Daniel Hoberman, Age: 18
Saint Anthony’s High School, New York
Project Title: Mapping the Mind: Quantifying the Relationship Between Access to Healthy Foods and Depression in Southeastern Pennsylvania via Measurement Error-Adjusted Poisson Regression Modeling
Sayeed Hossain, Age: 18
Spackenkill High School, New York
Project Title: Probing Quantum Gravity Signatures: Sensitivity Curves for Novel Interferometer Topologies for the QUEST Experiment Using FINESSE
Neil Xuan Hu, Age: 17
Temple City High School, California
Project Title: Development of an Innovative System To Reduce Ultrafine Particle Ingress Into Vehicle Cabins
Angie Huang, Age: 18
East Ridge High School, Minnesota
Project Title: Entanglement Sudden Death via Repeated Entanglement Swapping
Benson Lu Huang, Age: 17
Half Hollow Hills High School West, New York
Project Title: BLADE: Bioimpedance-Enabled Laparoscopic Articulated Dual-Purpose Endowrist System for Force Sensing and Anomaly Detection in Robotic Surgery
Sophie Katherine Huang, Age: 17
Hackley School, New York
Project Title: Deleting DNA Damage Repair Proteins Exo1, Sgs1, Rad24 and Rad9 Restores Cell Viability in Cdc13-null Candida glabrata
Pax Lu Huybers, Age: 18
Cambridge Rindge & Latin School, Massachusetts
Project Title: Estimating Ocean Wind Speed From Sea Surface Imagery Using Convolutional Neural Networks
Yena Hwang, Age: 18
Saint Anthony’s High School, New York
Project Title: Mechanical Activity of Skeletal Muscle Suppresses Lung Cancer Cell Migration Through Myokine-Mediated Pathways
Liah Igel, Age: 17
Bronx High School of Science, New York
Project Title: Human Cell-Based Assay and Mouse Tissue Analysis To Study FSHR Signaling in Parkinson’s Disease
Michael Iofin, Age: 17
Trinity School, New York
Project Title: Quasiconformal Maps and Random Meromorphic Functions
Anagha Lakshmi Iyer, Age: 17
American Heritage School, Florida
Project Title: A Novel Approach to Sustainable Concrete Engineering: Mechanochemical Activation of Local Waste Materials for CO2 Reduction
Eli Jacob, Age: 18
Herricks High School, New York
Project Title: Misinformation in Shaping Ethical Attitudes Toward AI-Centered Academic Misconduct via Social Media
Olivia Emma Jacobson, Age: 18
Roslyn High School, New York
Project Title: Parties in the USA: The Impact of Political Party Affiliation Strength and Party Alignment on Perceptions of Bipartisan Candidates
Vasu Jain, Age: 17
Edgemont High School, New York
Project Title: Identification of Chromatin Modification Regulators Implicated in Cancers Through CRISPR Screening
Claire Jiang, Age: 18
Bergen County Academies, New Jersey
Project Title: A Novel In Vitro Cell Culture Model for Juvenile Idiopathic Arthritis
Congyi Lucas Jiang, Age: 17
St. Mark’s School, Massachusetts
Project Title: Design of an Ergonomic Active Spinal Exoskeleton for Lifting Assistance
Billy Jin, Age: 19
Portsmouth Abbey School, Rhode Island
Project Title: GradCAM Analysis Reveals Deep Learning Models Misclassify Benign-Appearing Melanomas Based on Possible Architectural Shortcomings Instead of Misdirection Attention
Everett Jin, Age: 18
St. Mark’s School of Texas, Texas
Project Title: Behavioral Characterization of Zebrafish Seizures for Epilepsy Modeling
Henry Jin, Age: 18
Greenwich High School, Connecticut
Project Title: Bridging the Sim-to-Real Gap in Autonomous Drone Control via Curriculum-Scheduled Domain Randomization
Sophia Yinghan Jin, Age: 17
Stuyvesant High School, New York
Project Title: Coloring-Based Knot Invariants in Projective Space
Serin Jo, Age: 17
Roslyn High School, New York
Project Title: Design of a Lightweight Algorithm for Robust Mass Spectrometry Peak Detection
Addison N. Johnson, Age: 17
Martin Luther King Jr. Magnet High School, Tennessee
Project Title: Octopamine Localization Within the Antennal Sensorimotor System of Drosophila melanogaster
Tyler Cale Johnson, Age: 18
Governor John R. Rogers High School, Washington
Project Title: Shape-Shifting Flight: Exploring the Aerodynamic Performance of a Novel Trailing Edge Variable-Camber Morphing Wing System Implemented in a Flying Wing UAV
Julianna Anastasia Jones, Age: 17
North Carolina School of Science and Mathematics, North Carolina
Project Title: Characterization of Flow in Asymmetric Geometries for Valveless Flow Rectification in Insulin Delivery Microfluidic Systems
Varini Kadakia, Age: 17
Archbishop Mitty High School, California
Project Title: Autonomous Drone-Based System for Outdoor Air Pollution Mitigation
Edward Kang, Age: 17
Bergen County Academies, New Jersey
Project Title: RetinaMind: Convergent In Silico and In Vitro Evidence for the Retina as a Novel Biomarker in the Early Diagnosis of Neurodevelopmental Disorders
Brij Kapadia, Age: 17
Columbia Grammar & Preparatory School, New York
Project Title: Percived Negative Energy Density Hawking Radiation Near Black Holes: A Tensorial Derivation
Saurish Kapoor, Age: 17
Princeton High School, New Jersey
Project Title: A Deep Learning Approach for an Early and Non-Invasive Diagnosis of Cardiovascular Disease in Cattle Using Retinal Fundal Images
Khushi Karthikeyan, Age: 18
Ardsley High School, New York
Project Title: The Supermassive Problem: Probing Potential Stellar Formation Pathways of Intermediate-Mass Black Holes
Maxwell Kesselheim, Age: 18
The Roxbury Latin School, Massachusetts
Project Title: Framing Policy Through Humor: A Computational Analysis of Reddit Memes
Lucienne Sophie Keyoung, Age: 18
Manhasset High School, New York
Project Title: Tunable Morphology of Zero-Waste Cellulose Nanofiber Hydrogels via a Novel Gelatin-Mediated Ice Inhibition Mechanism for Sustainable Agriculture and Water Remediation
Alex Kidangathazhe, Age: 17
Stillwater High School, Oklahoma
Project Title: Transforming Natural Phenolics Into Bactericidal Therapeutics Using a Systems-Guided Stress Response Framework
Eashan Kosaraju, Age: 17
Solon High School, Ohio
Project Title: A Data-Driven Framework for Quantifying County-Level Structural Disadvantage and Disparities in Premature Mortality
Mythili Venkata Kota, Age: 17
McNair Academic High School, New Jersey
Project Title: Engineering a Novel Electrochemical Biosensor Using a Self-Healing ZnO Quantum Dot Matrix With MIP Technology for Lysozyme Detection
Soneesh Kothagundla, Age: 17
South Forsyth High School, Georgia
Project Title: Hard To Reach or Hardly Reached? Investigating Use of Lung Cancer Screening Among Eligible U.S. Adults Receiving Other Cancer Screenings
Aaron Eli Krasinski, Age: 18
Bronx High School of Science, New York
Project Title: A Novel Deep Learning Approach to the Health Crisis of Industrial Production in Space: Neural Network Classification and Glymphatic Biomarker Analysis of Spaceflight-Associated Neuro-Ocular Syndrome for Pre-Flight Crew Screening
Rushil Kukreja, Age: 16
Thomas Jefferson High School for Science and Technology, Virginia
Project Title: Preparing for the Next Carrington: Spatiotemporal Agent-Based Modeling for Safeguarding Satellite Infrastructure Under Extreme Space Weather Disturbances
Aiden Kwon, Age: 18
Palos Verdes Peninsula High School, California
Project Title: Revolutionizing Turbulence Studies: Novel Low-Cost Zero Mean-Flow Chamber Design and Computational Analysis of Reynolds Stress Tensor
Sam Land, Age: 17
Bronx High School of Science, New York
Project Title: Novel Characterization of COMT Gene Polymorphism Effects on Resting-State fMRI Network Segregation: A Breakthrough for Personalized Mental Health Treatment
Diego Benjamin Landeros, Age: 18
Lane Technical High School, Illinois
Project Title: Targeted Nitroisoxazole-Based GPX4 Inhibitor Drug Conjugate for Ferroptosis Induction in Chemoresistant Tumors
Darren Lau, Age: 18
Academy at the Lakes, Florida
Project Title: AuRING: A Novel Augmented Reality Intraoperative Neurosurgical System Using a Dual Discriminator Bayesian-Structural Similarity Generative Adversarial Network (D2BS2GAN) for Real-Time Brain Shift Compensation
Eun Jae Lee, Age: 18
Peachtree Ridge High School, Georgia
Project Title: Silent Signals: Boronic Acids Quench E. coli Quorum Sensing
Franklin Lee, Age: 17
Jericho Senior High School, New York
Project Title: Dual-Pathway Fusion of EHRs and Knowledge Graphs for Predicting Unseen Drug-Drug Interactions
Jaeho Lee, Age: 18
Spring Branch Academic Institute, Texas
Project Title: Affine Group of Integers Modulo n, Conjugacy Classes and Representations
Jooa Zoe Lee, Age: 18
Lexington High School, Massachusetts
Project Title: Multi-Omics Identification of SDHA Amplification as a Non-Invasive Biomarker in Saliva-Derived ctDNA From Non-Smoker Lung Cancer Patients
Madeline R. Levorson, Age: 17
Thomas Jefferson High School for Science and Technology, Virginia
Project Title: Novel Antimicrobial Treatments Designed With Discovered Lytic Bacteriophages Evaluated Through a Rapid Screening Protocol and an In Vivo Galleria mellonella System
Caroline Li, Age: 17
Thomas Jefferson High School for Science and Technology, Virginia
Project Title: Improving the Detection Sensitivity of Calcium Transients in Densely Labeled Neuronal Tissue Through Pinhole Illumination: A Low-Cost Approach
Ella Li, Age: 18
Saratoga High School, California
Project Title: Developing a High-Resolution, Cost-Effective, Saliva-Based HLA Typing Method With Long-Range PCR To Detect Autoimmune Disease Susceptibility
Mary Meijia Li, Age: 17
Hume-Fogg Academic High School, Tennessee
Project Title: Linking Early Life Adversity to Epigenetic Change: A Meta-Analysis of DNA Methylation as a Molecular Memory of Childhood Trauma
Sophia Li, Age: 18
John L. Miller Great Neck North High School, New York
Project Title: Closing the Shade Gap: Advancing Environmental Equity Through Understanding Tree Canopy Disparities in Redlined Communities With i-Tree
Leo Lian, Age: 18
Lake Washington High School, Washington
Project Title: Bridging the Justice Gap for Pro Se Civil Rights Plaintiffs: AI-Assisted Complaint Drafting Guided by Analysis of 3,750 Federal Cases
Frances Liang, Age: 17
The Nueva School, California
Project Title: PLI-Analyzer: A Novel Platform for Quantitative Assessment of Structural and Biological Accuracy in AI-Predicted Protein-Protein Complexes
Sophia Liang, Age: 17
Centennial High School, Maryland
Project Title: Pharmacologic Soluble Guanylate Cyclase Activation for Suppression of Epithelial-Mesenchymal Transition in Retinal Pigment Epithelial Cells: Implications for Wet Age-Related Macular Degeneration
Aaron Lin, Age: 17
Ladue Horton Watkins High School, Missouri
Project Title: The Geometry of a Counting Formula for Deformations of the Braid Arrangement
Helen Lin, Age: 18
Bronx High School of Science, New York
Project Title: Human Intervertebral Disc Degeneration, Sex and Aging Increase Alpha-1 Antitrypsin Expression in Intervertebral Discs
Jia Tong Lin, Age: 17
Yorba Linda High School, California
Project Title: Walking Assistant: Automated Exoskeleton With Flexible-Rigid Coupled Hip Joint and Spine
Matthew Lin, Age: 17
Roslyn High School, New York
Project Title: Using Bayesian Optimization To Design Conductive PEO-Based Mixed-Graft Block Copolymers
Christina Xinyi Liu, Age: 18
The Lakeside School, Washington
Project Title: Applying Explainable AI To Understand How Stellar and Planetary Parameters Impact Exoplanet Habitability
Elaine Liu, Age: 17
Syosset High School, New York
Project Title: The Effects of Apology Strategies on the Spread and Intensity of Cancel Culture Incidents
Geoffrey Liu, Age: 18
Glenda Dawson High School, Texas
Project Title: A Gamified Go/No-Go Paradigm for the Epilepsy Monitoring Unit
Grace Chenxin Liu, Age: 17
Syosset High School, New York
Project Title: Evaluating Gender Differences in the Effects of Ambiguity and Misperception on Entrepreneurship in Three Business Development Stages: A Panel Data Analysis
Isabel Shuan Liu, Age: 17
Liberal Arts and Science Academy, Texas
Project Title: A Novel Biomarker-Integrated Machine Learning Model in Chemotherapy-Induced Cardiotoxicity Risk Prediction
Jiayi Michael Liu, Age: 18
The Loomis-Chaffee School, Connecticut
Project Title: Differentiation and Functional Evaluation of Human-Induced Pluripotent Stem Cell (hiPSC)-Derived Cerebral Organoids To Model the AUTS2 Variant
Kevin Liu, Age: 17
Jericho Senior High School, New York
Project Title: Integrative Structural Modeling and Molecular Dynamics Simulations Reveal Novel Insights Into Autism SORCS3 Missense Mutations
Louis Liu, Age: 17
University High School, Arizona
Project Title: FallPoint: Fall Detection With 4D mmWave Radar Using PointNet and a Recurrent Neural Network
Mason Liu, Age: 18
Thomas S. Wootton High School, Maryland
Project Title: Developing a Novel BMS-986158 and Flavopiridol Combination Therapy for Treating Pediatric Brain Tumors
Anthony Low, Age: 17
Arnold O. Beckman High School, California
Project Title: A Novel 0D/2D Composite Phase Change Material for Thermal Management in High-Performance Computing
Lauren Low, Age: 18
Northwood High School, California
Project Title: A Novel Sparse-IMU Convolutional Neural Network for Real-Time Hip Kinematics in Exoskeleton-Augmented Gait
Ella Lu, Age: 17
North Carolina School of Science and Mathematics, North Carolina
Project Title: Compositional Analysis of Visual Art Structure
Kevin Lu, Age: 17
Bellarmine College Preparatory School, California
Project Title: AEGIS: Security Sandboxing Meets Mechanistic Interpretability To Defend Against Prompt Injection Attacks
Samuel Lu, Age: 18
Rowland Hall, Utah
Project Title: RPE Senescence and Age-Related Macular Degeneration: An Investigation of the Small GTPase ARF6 as a Potential Target for AMD Pathogenesis
Frank Lucci, Age: 18
BASIS San Antonio Shavano Campus, Texas
Project Title: SubArc: An Inexpensive, High Resolution, Open Source, Absolute Magnetic Rotary Encoder
Kai Lum, Age: 17
BASIS Independent Fremont, California
Project Title: Extremal Structural Results for Feedback Arc Sets and Graph Inversions
Anna Luo, Age: 17
Canyon Crest Academy, California
Project Title: Allelopathic Effects of Cynara cardunculus on Native Coastal Sage Scrub Species
Emma Luo, Age: 17
Northville High School, Michigan
Project Title: Steep Monetary Delay Discounting in Opioid Use Disorder: Application of the Rachlin Hyperbolic Model
Aliyah Majeed-Hall, Age: 18
The Potomac School, Virginia
Project Title: TRACE-Stem: A 222Rn-Calibrated Mechanistic Model of Methane (CH4) and Carbon Dioxide (CO2) Transport in Tree Stems
Rhea Malhotra, Age: 18
Stuyvesant High School, New York
Project Title: Identifying Therapeutic Gene Targets for Cataract and Glaucoma
Elias Malionek, Age: 18
Briarcliff High School, New York
Project Title: The Effects of Education of Interpersonal Relationships and Positive Masculinity in a Group Environment Led by a Same-Sex Peer With Adolescent Males on Depression, Self-Esteem and Ideologies of Masculinity
Finnegan McGill, Age: 18
Tanque Verde High School, Arizona
Project Title: A-BiRD: An Automated Bird Recognition Device for Acoustic Monitoring and Conservation
Alexander Miller, Age: 17
Woodbridge High School, California
Project Title: Universal Quantum Error Mitigation via Random Inverse Depolarizing Approximation
Yashnil Mohanty, Age: 17
Westmont High School, California
Project Title: Physics-Guided Neural Forecasts of Nearshore Harmful Algal Blooms in the California Current System
Benjamin Drew Moses, Age: 18
Paul D. Schreiber High School, New York
Project Title: Symptoms of Depression and Anxiety Among Survivors of Childhood, Adolescent and Young Adult (CAYA) Cancer
Natalie Muro, Age: 18
William J. Palmer High School, Colorado
Project Title: A Novel Field-Based Approach to Reducing Harmful Algal Blooms in Freshwater Ecosystems
Seth Jacob Nabat, Age: 18
William Howard Taft High School, California
Project Title: Learning Broken Symmetries With Approximate Invariance: A Novel Dual-Subnetwork Approach to Classifying Particle Collision Events
Ananya Gulur Nagendra, Age: 18
Plano East Senior High School, Texas
Project Title: Utilizing Ants To Mitigate MSW Landfill-Generated Methane Production Through Novel Aerobic Digester System for Anthropogenic Food Waste Decomposition
Siddharth Nair, Age: 17
Yorktown High School, New York
Project Title: Large-Scale Plastic Detection Pipeline via Machine Learning-Augmented Remote Sensing
Nived Nandakumar, Age: 17
Thomas Jefferson High School for Science and Technology, Virginia
Project Title: A Closed-Loop Deep Generative Model for the Inverse Design of Radiation-Resistant Polymers
Sharanya Sanjay Natarajan, Age: 18
Edgewood Junior/Senior High School, Florida
Project Title: An Integrated Detection and Delivery System To Abate Contaminants in Water Bodies
Paarth Nawani, Age: 18
Cupertino High School, California
Project Title: A Low-Cost Non-Mydratic Retinal Imaging System With a Multistage Deep Learning Pipeline for Automated Screening of Glaucoma
Eleanor Nayden, Age: 18
Princeton High School, New Jersey
Project Title: Impact of Political Allegiance on H-1B Visa Acceptances to the U.S.: An Analysis of the Relationship Between UNGA Voting Alignment and H-1B Visa Acceptances to the United States
Bach Ngo, Age: 17
Frazer School, Florida
Project Title: Hexa?ssa: Deep Strategic AI for Complex Real-World Decision Making
Max Hung Nguyen, Age: 17
Leland High School, California
Project Title: Star2Planet: Decoding and Predicting the Stellar Signatures of Planet Formation
Lindsey Liang Niu, Age: 17
Monta Vista High School, California
Project Title: Developing PDMS Microfluidic Sensors for Precise Micro Blood Flow Measurement To Advance Cardiovascular Diagnosis in Low-Income Regions
Olivia Grace Nostro, Age: 17
Brooklyn Technical High School, New York
Project Title: Effects of Non-Pharmacological Treatments on Seizure Duration in Bang-Sensitive Drosophila melanogaster Mutants
Suzuko Ohshima, Age: 18
North Hollywood High School, California
Project Title: Biophysical Characterization of SUN2-Pro-Macrobody Interactions Elucidates Multimerization Dynamics and Complex Stability
Willa Olson, Age: 17
Yorktown High School, New York
Project Title: The Effect of Endocrine-Disrupting Chemicals on the Social Behaviors and Testosterone Levels of the North American River Otter (Lontra canadensis)
Viktor Osadsky, Age: 18
Exeter High School, New Hampshire
Project Title: Scoring Radiography Collimation: Quantifying Background Impact Using Neural Networks
Sritej Sai Padmanabhan, Age: 17
North Allegheny Senior High School, Pennsylvania
Project Title: Linking Goals to Learning: A Novel Goal-Inclusive Kalman Filter Framework Reveals That Goal Uncertainty Attenuates Sensorimotor Adaptation
Suhani Pahuja, Age: 17
Monta Vista High School, California
Project Title: Long-Term Cardiovascular and Mortality Risk in Patients With Preexisting Arrhythmia Post SARS-CoV-2 Infection
Aarthi M. Palaniappan, Age: 17
Herricks High School, New York
Project Title: Elucidating the Protective Role of Wnt4 Signaling and Gene Suppression in Modulating Fibrotic and Calcific Pathways in Calcific Aortic Valve Disease
Rayhan Papar, Age: 18
The Woodlands College Park High School, Texas
Project Title: Sim-to-Real for Autonomous Tumor Resection via Minimally Invasive Robotics
Lila Lewis Papavasiliou, Age: 18
Thousand Oaks High School, California
Project Title: Identifying the Existence of Unconscious Gender Bias in the Perception of Political Speakers Using EEG
Medha Pappula, Age: 17
Thomas Jefferson High School for Science and Technology, Virginia
Project Title: Identifying Underlying Brain Connections in Pediatric ADHD: A Pathway to Early Diagnosis and Reduced Secondary Effects
Kaya Parikh, Age: 17
Hunter College High School, New York
Project Title: Ozempic? and Counterfeit Ozempic in Novel Triple-Readout Drosophila Model With Type-2 Diabetes and Obesity
Natalie Partridge, Age: 18
Ossining High School, New York
Project Title: Reading Interventions Foster Prosocial Behavior Development in Young Children
Siddharth Pasari, Age: 17
Hunter College High School, New York
Project Title: Development of N-glycan Microarrays as Sensors for Glycan Binders
Arnav Pemmaraju, Age: 18
William A. Shine Great Neck South High School, New York
Project Title: CRE-LogicSim: A Surrogate Modeling Framework for Interpreting Cis-Regulatory Element Function in Deep Sequence Models
Aashritha Penumudi, Age: 17
Thomas Jefferson High School for Science and Technology, Virginia
Project Title: A Novel Approach to Understanding the Structural Basis of Ribosome Stalling by AMD1 and Cellular Arresting Peptides
Zeviel Pineda, Age: 18
Veterans Memorial Early College High School, Texas
Project Title: Accelerating Whole-Brain Axonal Mapping Through Supervised Machine Learning and Proof of Concept in a Familial Alzheimer’s Disease Mouse Model
Karthik Prasad, Age: 18
Illinois Math and Science Academy, Illinois
Project Title: On Yetter-Drinfeld Modules Over the Pansera Algebras
Cynthia Qian, Age: 18
Jericho Senior High School, New York
Project Title: Computational Discovery of Marine Plastic-Degrading Enzymes Enhanced by Deep Eutectic Solvents
Vallabh Ramesh, Age: 18
duPont Manual Magnet High School, Kentucky
Project Title: Next-Gen Smart Materials: Thermo-Responsive and Conductive 3D Printable Polymer Gels for Diverse Applications
Elijah Renner, Age: 17
Thetford Academy, Vermont
Project Title: Pathformer: Large Language Models for Automated Billing Code Assignment in Multi-Institutional Pathology Reports
Ryan Sean Rezaei, Age: 18
Canyon Crest Academy, California
Project Title: Omni-Prot: Unifying Protein Function Prediction With PLM-Centric Fusion
Azimullah Rifai, Age: 18
Poolesville High School, Maryland
Project Title: Identification and Functional Validation of Single-Cell Resolved Myeloid Reprogramming Drivers in the Prostate Cancer Bone Metastatic Niche
Emily Ann Salemo, Age: 17
Harrison High School, New York
Project Title: The Effect of α-Tocopherol on Locomotor Ability of The Drosophila melanogaster Mutant for Glutathione S-Transferase Theta 3
Shanza Sami, Age: 17
West High School, Iowa
Project Title: SPECO: A Novel Multiparametric Methane Forecasting and Mitigation System Using Quantum Long Short-Term Memory and Sonophotoelectrochemical Oxidation
Akshat Santhana Gopalan, Age: 18
John P. Stevens High School, New Jersey
Project Title: TARGen: Novel Target-Aware Deep-Generative Framework for De Novo Therapeutic Antibody Design Develops Antibodies Targeting the Dark Kinome
Moitri Santra, Age: 16
Oviedo High School, Florida
Project Title: Development of an Industrially Viable Neutral pH Oxytetracycline Nanocarrier for Citrus and Stone Fruit Disease Management
Samuel Siddhartha Sastry, Age: 18
The College Preparatory School, California
Project Title: Folding and Reconfiguration of DNA Origami Book Structures
Aditya Sengupta, Age: 17
Bellevue High School, Washington
Project Title: ForeCAT: Advancing Clear Air Turbulence Prediction for Aviation Safety With Atmospheric Physics-Informed Neural Networks and Spatiotemporal Weather Data
Noah Michael Senzon, Age: 18
North Carolina School of Science and Mathematics, North Carolina
Project Title: Evaluating Kudzu (Pueraria montana) as a Sustainable Fiber for Thermal Insulation
Ananya Shah, Age: 17
Edgemont High School, New York
Project Title: A Comparison of Precinct and District Voting Data Using Persistent Homology To Identify Gerrymandering in North Carolina
Ashka Shah, Age: 17
Jericho Senior High School, New York
Project Title: Selective Dual Inhibition of β-Catenin in Wnt-Driven Cancers via Gid8-Assisted Translocation and a Precision Peptide-Based Gene Therapy
Nikhil Shah, Age: 18
Syosset High School, New York
Project Title: Examining the Impact of the Federal Sentencing Guidelines on Racial Disparities in Federal Sentencing
Iris Shen, Age: 17
The Woodlands College Park High School, Texas
Project Title: Assessing Marine Bivalves as Novel Invertebrate Models for Targeting Anti-Apoptotic BCL-2 Family Proteins in Blood Cancer: The In Vivo Effects of Ursolic Acid and Gossypol Acetic Acid on Tumor Cells in Mercenaria mercenaria
Lily Shi, Age: 17
The Harker School, California
Project Title: Enhancing Medical Explainability in Deep Learning for Age-Related Macular Degeneration Diagnosis
Aditya Shivakumar, Age: 18
The Harker School, California
Project Title: Ultra Low-Cost, Field-Deployable Arsenic(V) Detection and Adaptive Hotspot Mapping With Methylene Blue-Gold Nanoparticle Colorimetry and Smartphone Spectroscopy
Rohan Shivakumar, Age: 17
Viewpoint School, California
Project Title: A Novel Early-Warning Signal of Wildfire Spread Using Vegetation Stress at the Edge of Fire Fronts
Shawnak Shivakumar, Age: 17
Menlo Atherton High School, California
Project Title: Drugging the Undruggable: AI-Enabled Discovery of a Novel Cryptic Pocket and Inhibitors in Oncogenic eIF4E
Elizabeth Lilian Singh, Age: 17
Westlake High School, New York
Project Title: A Novel Epigenetic Pathway to Reversing Pulmonary Arterial Hypertension? Investigating the Regulating Role of UHRF1 in Smooth Muscle Cells
Ruhaan Singh, Age: 17
Farragut High School, Tennessee
Project Title: Utilizing a Temporal Sequence Transformer To Effectively Forecast Streamflow Across Diverse Hydroclimatic Regions in the United States
Indira Rajyalakshmi Sivaraj, Age: 16
Elk River Area Senior High School, Minnesota
Project Title: Uncovering Atomic-Level Insights in Metabolic Drug-Target Receptors Using Interpretable Machine Learning
Sebastien Sobeih, Age: 18
Phillips Exeter Academy, New Hampshire
Project Title: The Cross-Dependent PDFS Model and Its Application: Smagorinsky-LES Inspired Subgrid-Scale Models and Multiscale Cascade for Transfer of “Volatile Energy” Within Financial Markets
Dhruvika M. Solanki, Age: 17
Morgantown High School, West Virginia
Project Title: Theory-Trained Neural Networks for Robust Arrhythmia Classification
Kian Daniel Soleymani, Age: 17
John L. Miller Great Neck North High School, New York
Project Title: AI-Powered Conversational Tool for Early Stage Cognitive Decline
Alexis Solomon, Age: 17
Columbia Grammar & Preparatory School, New York
Project Title: The Role of Adolescent Sports Participation in Behaviors and Social Functioning in Young Adulthood
Andy Song, Age: 19
Phillips Exeter Academy, New Hampshire
Project Title: Investigating the Molecular Mechanisms of TCERG1 SNP rs79727797 in Modifying Huntington’s Disease Onset
Frederick Song, Age: 17
Solon High School, Ohio
Project Title: Trends in the Use of Reirradiation for Second Primary Breast Cancer
Siddharth Sridharan, Age: 18
Little Rock Central High School, Arkansas
Project Title: The Neurobiology of Voluntary Exercise: A Novel Approach To Alleviate Chemobrain by Promoting Hippocampal Neurogenesis
Cole Jacob Stern, Age: 17
John F. Kennedy High School, New York
Project Title: Investigating the September 29, 2023, Tri-State Flooding Event: A WRF-Based Analysis of Tropical Storm Ophelia, Elevated Sea Surface Temperatures and Their Role in Enhancing Extreme Rainfall
Uma Maya Sthanu, Age: 17
Westwood High School, Texas
Project Title: Glia-Neuron GPCR Signaling as a Therapeutic Route to Axon Regeneration: cAMP-PKA Activation Elevates Excitability and Regrowth in Neurons
Emma Elise Su, Age: 17
Herricks High School, New York
Project Title: Developing a Novel Adaptive Tuning Module for Real-Time Frequency Correction in Radiofrequency Coils During Concurrent TMS-fMRI
Kevin William Sun, Age: 17
Andover High School, Massachusetts
Project Title: Printing 2D MXene-Based Chipless Radio Frequency Identification Tags To Enable Plastic Waste Sorting for Recycling
Rebekah Rose Switzer, Age: 18
North Carolina School of Science and Mathematics, North Carolina
Project Title: Tannic Acid-Loaded pHEMA-Quaternary Chitosan Hydrogels for Use as Antimicrobial Contact Lenses
Eric H. Tang, Age: 18
Little Rock Central High School, Arkansas
Project Title: Comparison of the Presence of Heavy Metal Resistance Genes in Salmonella enterica and Their Association With Antibiotic Resistance
Kaavya Tatavarty, Age: 17
Henry M. Gunn High School, California
Project Title: Personalized Cloud-Based Semg-to-Haptic System To Enable Long Distance Communication for Usher Syndrome
Cooper Taylor, Age: 18
Greenwich Country Day School, Connecticut
Project Title: Lightweight Modular Dual-Tilt VTOL UAV: Design, Validation and Long-Endurance Performance
Hunter James Taylor, Age: 18
Dutch Fork High School, South Carolina
Project Title: The Implementation of Ostracods in Aquaculture Greenwater Systems
Abigail Thomas, Age: 17
Herricks High School, New York
Project Title: Examining the Pathway of Rab8-Mediated Trafficking of GluA1-AMPARs in Response to In Vitro Chemical LTP Induction in Wildtype and Lrrk2G2019S Striatal and Cortical Neurons
Serina Tomioka, Age: 17
Ardsley High School, New York
Project Title: Characterizing the Spatial Dynamics of CD44 and Amyloid-Beta Plaques in Human Alzheimer’s Disease Brain
Uyen Tran, Age: 19
Bergen County Academies, New Jersey
Project Title: Effect of Tamoxifen and 17-β-Estradiol on Lung Adenocarcinoma Proliferation: What Do We Know About the Role of Sex Hormones in Lung Cancer?
Zoe Tran, Age: 17
Laguna Beach High School, California
Project Title: Development of a Novel Co-Expression-Dependent Direct Protein Interaction Mapping Method
Maya Julia Trutschl, Age: 18
Caddo Parish Magnet High School, Louisiana
Project Title: Automated Prediction and Prevention of Pressure Injuries Using Machine Learning and Thermal Sensing: A Clinical Validation Study
Sam Tummala, Age: 17
Chantilly High School, Virginia
Project Title: From Waste to Worth: Transforming Resistant Starches From Waste Rice Into a Single-Use Plastic Alternative and Controlled-Release Organic Fertilizer
Atharva Tyagi, Age: 18
Woodbridge Academy Magnet School, New Jersey
Project Title: From Mutation to Cure: A Prime Editing Approach to Universal Genetic Rescue in Familial Hypercholesterolemia
Aadhi Umamageswaran, Age: 17
West High School, Utah
Project Title: Visualizing Animal Vocalizations for Species Identification
Luis Vidal, Age: 18
Arkansas School for Mathematics, Sciences & the Arts, Arkansas
Project Title: Designing Substrates To Test HELB as a Potential Therapeutic Agent Against Glioma and Colon Adenocarcinoma
Natalie Viderman, Age: 17
Hunter College High School, New York
Project Title: Hypoxia as a Novel and Non-Invasive Experimental Treatment Model for Congenital Dsyerythropoietic Anemia and Rare Erythroid Diseases
Emily Walch, Age: 18
Pelham Memorial High School, New York
Project Title: Testing a Domain-Specific Impact of English Language Cognitive Test Bias in Spanish Speakers in the United States
Alexander Wang, Age: 18
Millburn High School, New Jersey
Project Title: Bounds on the Number of Edges in Visibility Hypergraphs
Angela Wang, Age: 17
University School of Milwaukee, Wisconsin
Project Title: A Novel CNN-Based Approach for Early Alzheimer’s Prediction Using Linkage Disequilibrium Matrices From APOE Genetic Data
Brady Wang, Age: 18
Horace Greeley High School, New York
Project Title: Generation of Antibody Oligonucleotide Conjugates Using a Novel Conjugation Technology
Julang Wang, Age: 18
Friends Academy, New York
Project Title: Localized Metaresonators for Mid-Wave Infrared Spatial Light Modulators
Leon Wang, Age: 17
King School, Connecticut
Project Title: Repurposing Idiopathic Pulmonary Fibrosis Drugs To Treat Vascular Alzheimer’s Dementia: A Safe, Effective and Accessible Approach to Alzheimer’s Treatment
Lucas (Zihe) Wang, Age: 17
Los Gatos High School, California
Project Title: InnoColor Edge: A Real-Time Wearable System With Distilled Vision Transformer-Guided Recoloring for Color Vision Deficiency
Yanchen Wang, Age: 17
St. Francis Preparatory School, New York
Project Title: Characteristics and Risk Factors of Anomalous Sleep Experience (Sleep Paralysis) in American Adolescents
Otto Watson-Brown, Age: 17
Martin Luther King Jr. Magnet High School, Tennessee
Project Title: Using Foldit To Design Novel KNa1.2 (Slick) Channel Inhibitors
Haodong Wei, Age: 18
Cranbrook Kingswood School, Michigan
Project Title: LLM-Powered, Chain of Action (CoA)-Based, Multi-Agent Collaboration for Hexapod-Drone Systems
Mary Wei, Age: 18
Evergreen Valley High School, California
Project Title: A Fast and Accurate Method for Numerical Integration of Bandwidth-Limited Signals
Huxley Westemeier, Age: 18
St. Paul Academy & Summit School, Minnesota
Project Title: Integrity: Generalized Artificial Image Classification With Noise Domain Localization
Nolan H. Woo, Age: 18
Saratoga High School, California
Project Title: A Comparative Study of AI and Human Programming on Environmental Sustainability
Brad Wu, Age: 17
Arizona College Preparatory High School, Arizona
Project Title: A Brain-Computer Interface-Driven Forearm Exoskeleton With Adaptive Neuroregulation-Based Feedback for Stroke Rehabilitation
Flora Rain Wu, Age: 17
Guilderland Central High School, New York
Project Title: The Impact of Maternal Risk Factors and Drinking Water Contaminants on Cyanotic Congenital Heart Defects
Xi Zhen Wu, Age: 18
Bronx High School of Science, New York
Project Title: Exploring the Potential of Inhaled Tadalafil Liposomes for Pulmonary Arterial Hypertension
Anfeng Xie, Age: 18
St. Paul’s School, New Hampshire
Project Title: An Energy-Generating and Power-Storing Seashell: An Innovative Attempt To Increase Power Output While Lowering Cost
Arianna Aisi Xie, Age: 17
Shanghai High School International Division, China
Project Title: Enhancing Base-Editing Efficiency by DNA Gap Induction
Henry Xie, Age: 17
Westview High School, Oregon
Project Title: Distilling Empathy From Large Language Models
Sonja Xie, Age: 17
Scarsdale High School, New York
Project Title: Neurite Degeneration Induced by UK-5099 Inhibition of the Mitochondrial Pyruvate Carrier Reveals Metabolic Thresholds for Neuronal Integrity
Keith Xin, Age: 18
Whitney Young Magnet High School, Illinois
Project Title: High-Capacity Al3+/Fe3+-Crosslinked Nanocellulose Hydrogels for Arsenite Removal: A Zero-Waste Approach to Water Remediation
Tina Shuxin Xing, Age: 17
Ward Melville High School, New York
Project Title: Carbon-Aware Reserve Allocation and Checkpoint Scheduling for GPU Sustainability
Jenny Zhang Xu, Age: 18
Fairview High School, Colorado
Project Title: CaraG Nanoparticle, a Novel CRISPR/SaCas9 Delivery Vehicle To Disrupt ANGPTL3 and PCSK9 Genes for Hypercholesterolemia Treatment
Jerry Xu, Age: 17
Lexington High School, Massachusetts
Project Title: A Unified Protein Embedding Model With Local and Global Structural Sensitivity
Ryan Xu, Age: 17
Plano West Senior High School, Texas
Project Title: LibAssembler: A Neural Framework for Library-Constrained Reconstruction of 3D Part Assemblies From a Single 2D Image
Jonathan Yan, Age: 18
Sage Hill School, California
Project Title: Bioinformatic Analysis of Metastasis-Associated Metabolic Landscape Reveals an Oncogenic Role for the Transsulfuration Pathway
Sophia Yan, Age: 17
Newton South High School, Massachusetts
Project Title: Mapping Enhancer-Gene Interactions in the Human Brain Reveals Reduced Use of Enhancers for Synaptic Genes in Schizophrenia
Berkay Yilmaz, Age: 17
John P. Stevens High School, New Jersey
Project Title: DNA Chalk: Calcium Carbonate-Functionalized DNA Tensegrity Triangle Crystals for Targeted Drug Delivery
Alyssa Yu, Age: 17
Poolesville High School, Maryland
Project Title: When Epidemics Meet: Understanding Spatiotemporal Interactions of Two Pathogens on Metapopulation Networks via Reaction-Diffusion Dynamics
Amy Yu, Age: 17
White Station High School, Tennessee
Project Title: Exploring the Power-Performance Balance: GPU Frequency Scaling in AI Workloads
Qiuen Yu, Age: 18
The Lawrenceville School, New Jersey
Project Title: Advancing Phytoremediation of PFAS in Biosolids: Soil Condition Optimization and Nutrient Preservation
Tommy Yuan, Age: 18
Jericho Senior High School, New York
Project Title: A Genetic Algorithm Approach to Automated Strategy Acquisition in 2048
Alex Zhang, Age: 18
Cate School, California
Project Title: Prometheus: A Recursively Self-Improving NAS System
Celine Zhang, Age: 18
Phillips Exeter Academy, New Hampshire
Project Title: Designing Zero-Knowledge Proofs for Agent Motion Planning
Claire Zhang, Age: 17
Brentwood High School, Tennessee
Project Title: Tardigrades’ Cytoplasmic Abundant Heat-Soluble Proteins Serve as Membrane Protectors During Dehydration
Evan Zhang, Age: 17
The Harker School, California
Project Title: Self-Sensing Hydraulically Amplified Self-Healing Electrostatic Artificial Muscles With AI-Driven Control for Cardiac Assist
Kelly J. Zhang, Age: 18
Polytechnic School, California
Project Title: Sentinel-2 Image Classification of Mangrove Populations Change From Cyclone Amphan To Locate Communities in the Sundarbans Most Affected
Olivia Du Zhang, Age: 17
Kent Place School, New Jersey
Project Title: Adipocyte-Derived Extracellular Vesicles Reprogram Tumor Cells and Drive Stemness in Triple-Negative Breast Cancer
Serena Julissa Zhang, Age: 18
William G. Enloe High School, North Carolina
Project Title: Design and In Silico Validation of an Antigen-Conjugated Fc-Fusion Protein for the Treatment of Myasthenia Gravis
Shaohuan Zhang, Age: 18
Cranbrook Kingswood School, Michigan
Project Title: Generalizations of the Zesting Construction
Shuyue (Linda) Zhang, Age: 17
Scarsdale High School, New York
Project Title: Optimizing Gene Capture: A Direct Cloning Strategy for Large Genomic Fragments
Justin Zhao, Age: 19
Jericho Senior High School, New York
Project Title: Structural Insights Into the Hybrid Infection Strategy of Bacteriophage Peru-2
Max Zhao, Age: 17
Thomas Jefferson High School for Science and Technology, Virginia
Project Title: Improving Time-Series Flood Detection on Remote Sensing Satellite Imagery With Persistent Homology
Audrey Zheng, Age: 17
North Allegheny Senior High School, Pennsylvania
Project Title: Targeted Isolation of Tumor-Derived Extracellular Vesicles Using a Cocktail of Magnetic Nanospheres for Minimally Invasive Pancreatic Cancer Diagnosis
Lin Zheng, Age: 18
University School of Nashville, Tennessee
Project Title: Sex Differences in GABA-A Receptor Regulation of Dopamine Release in the Nucleus Accumbens and Its Role in Cocaine Use Disorder
Aiden Ruipeng Zhou, Age: 17
Western Academy of Beijing, China
Project Title: Flow Matching-Based Text-to-Speech for Low-Resource Automatic Speech Recognition Augmentation
Eric Zhou, Age: 18
Troy High School, Michigan
Project Title: Adaptive DAG-Based BFT Consensus Protocols Using Machine Learning
Liran Zhou, Age: 17
Jericho Senior High School, New York
Project Title: Novel Reconfigurable Straight-Spoke Triwheel Mechanism With Four-Bar Linkage for Optimal Stair Climbing
Bryan Zhu, Age: 18
Bellevue High School, WA
Project Title: Dimension Reduction for Smooth Convex Optimization via Color Refinement
Elena Tao Zhu, Age: 18
Upper Arlington High School, Ohio
Project Title: Intracellular Calcium Oscillation Promotes the Migration and Invasion of Liposarcoma Cells
我要了解STS！
更多信息可掃碼添加小師姐咨詢
讓我們恭喜以上獲獎的學生！結合STS的官方數據，我們可以發現今年比賽有以下特點：
今年，研究項目涵蓋20個類別，從動物科學到空間科學。其他學生則選擇專注于行為科學、生物化學和環境科學等領域。今年的前五大類別是↓
- 細胞與分子生物學
- 醫學與健康
- 計算生物學與生物信息學
- 計算機科學
- 工程
科學協會總裁兼首席執行官兼《科學新聞》執行出版人Maya Ajmera說：“他們的研究彰顯了推動科學探索未來發展的創造力、嚴謹態度與堅定決心。我們很榮幸能認可他們的成就，并支持他們在科學、技術、工程和數學領域持續追求卓越。”
再生元企業事務高級副總裁Christina Chan說道，“我們與STS的合作，旨在賦能年輕科學家，激勵他們運用自身的創造力與發明才能，推動解決全球面臨的重大挑戰。我們祝賀這些學者取得的成就，并期待見證他們各自的未來發展。”
1月21日，STS評委還將在Top300中進一步評選出Top40，之后入圍Top40的學生還將參加為期一周的STS決賽，爭奪高額獎金和國際榮譽！小師姐也會持續關注賽事動態并及時更新，記得關注＋星標【有方背景提升】，第一時間收到推送！
再生元科學天才獎 STS
Regeneron STS始創于1942年，由再生元冠名贊助，鼓勵年輕一代發明創造新科技和方法，改善人們的生活，改變世界。
在含金量和長遠價值的雙重誘惑下，STS成為了全美高中生乃至華人圈的必爭科研賽事之一。
在近兩年晉級STS半決賽的500多位學生中，有50-57%的入圍者錄取哈耶普斯麻，70-76%的學生成功進入TOP15美本！
1、適合學生
在美國及美國所有海外領土高中12年級學生，以及居住在海外的美國公民學生(需提交證明)具備資格申請。
- 目前就讀11年級的同學可以先開始準備項目，在下半年12年級上學期，即高中最后一年的學生進行申報申請。
2、參賽規則
STS必須是單人參賽并完成。
- 不可用已完成的團隊合作項目參賽；
- 不可將團隊項目刻意改成單人項目參賽；
- 可以與科研導師/大學生共同完成研究項目，但他們不能過多干預/直接影響學生單人完成項目的結果；
- 每位學生只能提交一個項目；
- 成果必須充分展示申請學生個人的想法。
3、參賽學科分類
行為和社會科學、生物化學、生物工程、細胞和分子生物學、化學、計算生物學和生物信息學、計算機科學、地球和行星科學、工程、環境科學、基因組學、材料科學、數學、醫學和健康、物理、植物科學和空間科學。
4、2025-2026新賽季時間線
#1
申請開放 2025年6月1日
學生可以在申請系統中在線申請
#2
申請截止日期 2025年11月6日
學生需要在截止日期之前提交申請和推薦，只能通過線上系統提交。截止后，原則上不接受任何形式、任何原因的修改
#3
TOP 300學者公布 2026年1月7日
#4
TOP 40入圍名單公布 2026年1月21日
#5
STS決賽周 2026年3月5-11日
#6
項目公開展覽 2026年3月8日
#7
頒獎典禮 2026年3月10日
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STS助力TA們翠錄夢校
在有方STS獲獎學員中，就有不少學員在收獲一段獨特的科研經歷的同時，還翠鹿夢校繼續深造！
曾參加過STS的Tony同學，在早申階段順利斬獲賓大Offer👇
有方Tony同學/ED錄取賓大
⭐計算機、數學、物理都參加了美國國家級競賽
⭐利用課余時間完成了“自傳感軟體機器人”項目，并一舉獲得ISEF、STS頂級科研賽事獎項
在采訪時，Tony同學坦言賓大想要的學生和其他藤校很不同。在賓大招生官的眼中，像STS這樣的實踐類比賽，相較于純粹的學術性競賽，還是更具說服力的。
Tony同學表示：“有方老師經過對歷年ISEF地區賽事的數據分析，發現在我所在的州做偏理不偏工的這種項目，他從課題創新性、實驗可行性及區域賽事特點等維度進行了專業分析，指出軟體機器人方向不僅更符合我們州的評審喜好，且這個課題是帶實驗的，是一個比較前沿的課題。巧妙地將興趣與參賽需求相結合，實現了二者的完美融合！”
“我曾以為，只要項目做得好，自然能脫穎而出，如同金子總會發光。然而事實并非如此，你得告訴人家它在發光。”Tony同學對自己的科研經歷有說不完的話，相信也正是感受到了他對科研的這份熱忱，所以才得到了賓大招生官的肯定！
科研是周期性的項目，需要較長的準備時間。如果你目前正值G11，STS絕對是在高中階段極限背提的不二之選！
如果你也想通過精準規劃提升自己的學術背景，趕緊掃碼添加小師姐獲得一對一的學術規劃！
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翰林賦能國際學術進階
全學科120+競賽｜學術科研｜IB/AP/A-LEVEL
培訓+美高雙資質，助力學員學術精彩！
